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Coronavirus Covid-19 (Read 689474 times)

Will Hunt

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#2000 Re: Coronavirus Covid-19
July 08, 2020, 01:37:16 pm
I'd thought it was known for some time that tiny airborne droplets (i.e. those which can travel further than a short distance) were a risk if you were present downwind or in a poorly ventilated space for a prolonged period - because the tiny airborne particles will carry fewer viruses then big droplets, so exposure needs to be longer to achieve an infectious dose.
This is why opening pubs and restaurants, car sharing, etc is a bad idea? Because distancing doesn't work in unventilated spaces?

This was in that contact tracing blog post that was linked to in pages past. Is this only now just becoming properly evidenced?

tomtom

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#2001 Re: Coronavirus Covid-19
July 08, 2020, 01:40:59 pm
I'd thought it was known for some time that tiny airborne droplets (i.e. those which can travel further than a short distance) were a risk if you were present downwind or in a poorly ventilated space for a prolonged period - because the tiny airborne particles will carry fewer viruses then big droplets, so exposure needs to be longer to achieve an infectious dose.
This is why opening pubs and restaurants, car sharing, etc is a bad idea? Because distancing doesn't work in unventilated spaces?

This was in that contact tracing blog post that was linked to in pages past. Is this only now just becoming properly evidenced?

Sentence 2 of the article if you looked at it:

“ WHO bows to pressure from scientists about risk from aerosol transmission”

Will Hunt

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#2002 Re: Coronavirus Covid-19
July 08, 2020, 02:01:55 pm
I'd thought it was known for some time that tiny airborne droplets (i.e. those which can travel further than a short distance) were a risk if you were present downwind or in a poorly ventilated space for a prolonged period - because the tiny airborne particles will carry fewer viruses then big droplets, so exposure needs to be longer to achieve an infectious dose.
This is why opening pubs and restaurants, car sharing, etc is a bad idea? Because distancing doesn't work in unventilated spaces?

This was in that contact tracing blog post that was linked to in pages past. Is this only now just becoming properly evidenced?

Sentence 2 of the article if you looked at it:

“ WHO bows to pressure from scientists about risk from aerosol transmission”

I read the article  ::)

My surprise is that this is only just becoming accepted. It was described on here over a month ago. My question (if you looked at it) was why the change in position now. Has the evidence only just now gone through peer review? Does the WHO require a large body of corroborating evidence to change its mind? Perhaps the WHO has been reluctant to acknowledge it until now because it means that economic restart will be hampered (not to mention the difficulty in communicating the new health message to "stay 2m apart unless you're indoors in which case don't be too long") - though of course, economic restart is not within their remit.
« Last Edit: July 08, 2020, 02:08:30 pm by Will Hunt »

petejh

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#2003 Re: Coronavirus Covid-19
July 09, 2020, 02:33:28 pm
So as per my posts on B3 from here: https://ukbouldering.com/board/index.php/topic,30489.msg603070.html#msg603070

and here:
://ukbouldering.com/board/index.php/topic,30489.msg603488.html#msg603488


There's now more evidence to back this up.

Preclinical research on NR and its role in covid-19 infected cells has now been released today in pre-print form, available here: https://www.biorxiv.org/content/10.1101/2020.04.17.047480v3

Note my disclaimers - I'm a shareholder in Chromadex (which are up 22% on this news)

Further research adding evidence to the B3 / NAD+ hypothesis.

https://twitter.com/FehrLab/status/1260342672688119810

Update on this. The next pre-clinical study was released last night US time. It reinforces the hypothesis that's been building around NAD depletion leading to worse outcomes from covid-19 infection; and the role of NAD augmentation using NR to slow virus replication.
https://finance.yahoo.com/news/chromadex-announces-study-results-highlighting-103600635.html
These are great times to be a mouse.
Human study coming soon..

(I'm an investor, I'm biased)

tomtom

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#2005 Re: Coronavirus Covid-19
July 13, 2020, 11:15:04 am
My friends in the Cotswolds have the recurring problem: they recover a bit then get ill again, and again. 5 bouts so far. They were fit and healthy triathletes in their late 50s.

petejh

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#2006 Re: Coronavirus Covid-19
July 13, 2020, 11:28:16 am
Hearing more and more stories about very fit people in their 50s and 60s suffering life-changing conditions. A climbing friend was telling me this the weekend about his super-fit friend in his 50s who caught covid and suffered a stroke due to it. He said out of all his friends in that age group this was the last person he'd have guessed would fare badly. Seems a lot of the outcome is down to the reaction of the individual's inflammatory response, which is hard to predict. 

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#2007 Re: Coronavirus Covid-19
July 14, 2020, 06:35:37 pm
Oof 1240 new cases today... I know the numbers fluctuate alot, but thats 9 days after the shops, bars and restaraunts were allowed to re-open....

edit - c400 - looks like the 1240 figure includes a load of previously uncounted pillar2 data from Wales... as you were :)
« Last Edit: July 14, 2020, 06:42:30 pm by tomtom »

Oldmanmatt

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#2008 Re: Coronavirus Covid-19
July 14, 2020, 07:36:43 pm
Hearing more and more stories about very fit people in their 50s and 60s suffering life-changing conditions. A climbing friend was telling me this the weekend about his super-fit friend in his 50s who caught covid and suffered a stroke due to it. He said out of all his friends in that age group this was the last person he'd have guessed would fare badly. Seems a lot of the outcome is down to the reaction of the individual's inflammatory response, which is hard to predict.


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#2009 Re: Coronavirus Covid-19
July 15, 2020, 08:25:45 am
Good recent episode of More or Less https://www.bbc.co.uk/sounds/play/p08kdnbp

Probably not that surprising, but more dirt on how shit the government 'testing' figures are. In particular they count tests as they're sent out to people (obviously no actual testing has taken place at that point), and they have now admitted that a full 2/3rds (or 2 million) of these posted home testing kits did not actually end up in a test happening (e.g. courier left testing kit in a puddle so it was unusable, went missing in post etc.)

Some interesting analysis of the swedish strategy too.

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#2010 Re: Coronavirus Covid-19
July 15, 2020, 10:22:24 pm
Just wondering with masks becoming compulsory in shops has anyone bought one that they can recommend? Been looking this evening and there seems to be a massive variation in materials used and costs.

tomtom

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#2011 Re: Coronavirus Covid-19
July 16, 2020, 07:35:43 am
Just wondering with masks becoming compulsory in shops has anyone bought one that they can recommend? Been looking this evening and there seems to be a massive variation in materials used and costs.

I’ve got a couple of cloth ones and Tbh I prefer the disposable type ones with earloops. I find them a bit lighter and less scratchy than the cotton ones (one made for me by mother in law) and they have a metal/bendy strip along one side to pinch over the nose a bit.

I got them online - and they’re the same brand as the ones my wife is given at work (NHS).

I use them like reusable ones - but ive only used them when dipping in and jut of a shop.

tomtom

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#2012 Re: Coronavirus Covid-19
July 19, 2020, 09:12:45 pm
COVID cluster in Lanarkshire. Based around a call centre carrying out... contact tracing for the NHS... couldn’t make it up..

https://www.bbc.co.uk/news/uk-scotland-glasgow-west-53465160

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SA Chris

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#2014 Re: Coronavirus Covid-19
July 20, 2020, 09:57:33 am
Doesn't sound good. I miss the old campsite at Achnahaird.

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#2015 Re: Coronavirus Covid-19
July 20, 2020, 10:53:48 am
My friends in the Cotswolds have the recurring problem: they recover a bit then get ill again, and again. 5 bouts so far. They were fit and healthy triathletes in their late 50s.

I’ve had three in total. The last, two weeks ago was the worst.  No respiratory problems thankfully but I was out of it for three days and am still recovering.  Much worse than the first bout back in March.

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#2016 Re: Coronavirus Covid-19
July 20, 2020, 11:33:34 am
Sorry to hear that Ben. Hope it fades now.

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#2017 Re: Coronavirus Covid-19
July 20, 2020, 11:42:45 am
A few days old but data from the ZOE/Kings symptom reporting app suggests that cases can be grouped by their early symptoms. These groups are good indicators of how serious a case is likely to become and whether it is likely to result in hospitalisation and ventilation. They remain good indicators even after considering age and existing conditions.

https://covid.joinzoe.com/post/covid-clusters

https://www.medrxiv.org/content/10.1101/2020.06.12.20129056v1

Tl;dr if you develop shortness of breath, neurological symptoms such as confusion and gastrointestinal symptoms such as diarrhoea, be very concerned.

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#2018 Re: Coronavirus Covid-19
July 20, 2020, 07:14:19 pm
Sorry to hear that Ben. Hope it fades now.

Yes - that sounds grim Ben :(

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#2019 Re: Coronavirus Covid-19
July 20, 2020, 07:59:57 pm
Thanks guys - I’m mostly OK now. Just have tinnitus, sore eyes and tiredness. Had a long walk round the park yesterday that felt tiring but hasn’t knocked me out thankfully. Having a real pint in a pub was amazing.


I did test the weekend before last after speaking with a GP to see if I had been infected twice or whether it’s a long term thing but somehow managed to balls up the scanning of the barcode on the sample and never got the results so did another today. I’m sure that’ll come back -ve so will do an antibody and a T-cell test if I can.

It weighs on the mind a bit. Like, have I got something that’s going to keep coming back?  I’d normally be doing press-ups and stuff in the morning and the odd run but just don’t have the energy.

Will keep you posted.


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#2020 Re: Coronavirus Covid-19
July 20, 2020, 09:56:51 pm
Shit Ben, I am so sorry to read all this; I had no idea. Get well and stay strong.

Will Hunt

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#2021 Re: Coronavirus Covid-19
July 24, 2020, 11:08:11 am
Not quite concrete evidence, but a promising development for users of crags and walls. Sharing holds maybe not the problem we thought it could be (provided you chalk up).
https://www.abcwalls.co.uk/news/chalk-deactivates-the-virus-on-holds/

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#2022 Re: Coronavirus Covid-19
July 24, 2020, 11:15:43 am
"So, if we put the chalk inside the body by, you know intravenously, like an injection or something, then the next day, the virus could just, kind of, vanish. And you experts are looking into that, right?".

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#2023 Re: Coronavirus Covid-19
July 24, 2020, 12:13:51 pm
I see the chalk where it knocks it out in a minute. One minute. And is there a way we can do something like that, by injection inside or almost a cleaning.  :devil-smiley:

Oldmanmatt

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#2024 Re: Coronavirus Covid-19
July 24, 2020, 01:50:30 pm
Yeah, but you can’t moan at people that don’t brush after an especially chalky session, now.
‘Coz they’re just doin a public service, ain’t they.

“Left it sterile for ya, mate.”

 

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